News for the Multiple Sclerosis Community

Possible myelin repair breakthrough?

I know this is from 2007, but the info came up again recently as human clinical trials are slated to start soon. Preliminary human trials started last year, and results were promising.

Reasearchers from the Mayo clinic link have genetically engineered a human antibody that reverses damage to myelin caused by MS--so far just the mouse form (EAE), and only a hanful of human volunteers. But if it is shown to work in a wider group of humans, and is considered safe and effective, then it is very promising indeed since it is only a one-time injection and starts to work in as little as 5 weeks.

Has anyone been able to find out more about this research? I would like to know if Mayo has started human trials yet, but haven't located any information on such trials. It does sound promising, except it is hard to get excited when only mice are involved at this point.

That is the latest news I have found : http://www.mayoclinic.org/news2008-rst/4768.html

I have been diagnosed for 4 years and have spent the past two in a wheelchair. My hope is that this research is on a faster track than the SPMS I have been strapped with.
Any idea where/how to volunteer on further trials for this research?

I too was diagnosed a little under four years ago with multiple sclerosis and am now in a wheelchair much of the time. I contacted the Mayo Clinic and was told that I needed to write a letter asking to be included in the upcoming clinical trials for this potential new drug. You can fax it to the neurology department, attention: neurology appointments - Linda at 507-284-2203. Let me know if you need any further information or if I can be of further assistance.
Best wishes,
Paul

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